ABSTRACT
New Cobalt(II) and Nickel(II) metal complexes of 2-aminothiazole (ATZ) and benzoate ion (BEN) ligands were synthesized under microwave irradiation. The empirical formulae and the structure of the complexes have been deduced from CHN analysis, electrical conductance, magnetic moment, electronic (DRS method), Infra Red spectra, TGA analysis, cyclic voltammetry and powder-XRD techniques. The low electrical conductance values indicate that the complexes are non-electrolyte (1:0) type. The electronic spectra and the magnetic moment indicate the structures of the complexes are found to be octahedral geometry. Infra Red spectra illustrate that 2-aminothiazole and benzoate ion is bonded to the metal ion in a monodentate approach. The antifungal activities of ligands and their cobalt(II) and nickel(II) metal complexes were studied aligned with the few microorganisms by agar - well diffusion method at 100,200 and 400 conc. µg/ml concentration. The prepared cobalt(II) and nickel(II) metal complexes show prospective action against the tested fungi as compared to free 2-aminothiazole ligand. The free radical scavenging action of the prepared complexes and the ligand has been resolute by measuring their interface with the stable free radical DPPH. The complexes have larger antioxidant activity as compared to the free ligand. DNA-binding properties have been calculated by fluorescence-emissions method. The obtained results suggest that the complexes powerfully bind to DNA because of metal complexes are well-known to speed up the drug action and the capability of healing agent which can repeatedly be enhanced leading coordination with a metal ion.
ABSTRACT
An experiment was conducted to study the effect of organic and inorganic fertilizers on plant height, plant spread and flower diameter of Gaillardia (Gaillardia pulchella). In Gaillardia the plant maximum height was recorded in the plot treated with 100 per cent recommended dose of NPK + press mud at 10 tones ha-1 followed by 75 per cent recommended dose of NPK + press mud at 10 t ha-1 at 45 days and 75 per cent recommended dose of NPK + press mud at 5 tones ha-1 at 15, 30 and 60 days. Highest plant spread was obtained at 30 and 45 days after planting in the treatments which involved 100 per cent recommended dose of NPK + press mud at 10 t ha-1 and at 60 days no significant differences were recorded. The combination of recommended dose of NPK + press mud at 10 t ha-1 produced maximum diameter of flower.
ABSTRACT
The antibacterial activity of various solvent extracts of medicinal plants was evaluated against the human pathogenic bacteria Escherichia coli, Klebsiella pneumonia, Bacillus subtilis Bacillus cereus, Salmonella typhi, Enterobacter aerogenes and Staphylococcus aureus by agar cup diffusion method. Methanol extracts of Clerodendrum inerme L., Terminalia chebula Retz., Curcuma amada Roxb., Anacardium occidentale L., Duranta repens L., Eucalyptus camaldulenis Dehnh and Euphorbia cotinifolia L. showed significant activity. The petroleum ether and chloroform extracts of Terminalia chebula, Curcuma amada and Piper betel also showed promising results. The antibacterial activity of promising plant extracts when compared with standard drugs streptomycin and gentamycin recorded siginificant inhibition. Phytochemical analysis of the different extracts of the screened plants indicated the presence of flavanoids, terpinoids, tannins steriodas, alkaloids and glysocides. The positive results of screening of medicinal plants for antibacterial activity forms primary platform for further phytochemical and pharmacological studies.
ABSTRACT
A two dimensional mathematical model was generated, representing a three unit fixed-fixed partial denture and its supporting structures. Second premolar and second molar were used as abutments with first molar as pontic. A load of 1 kg was applied to the occlusal surface of the casting. Stresses and displacement developed at various regions were analyzed with STAAD III/ISDS program. Maximum stresses were developed in the pontic and connectors with distal connector experiencing the maximum stresses. Stresses transmitted to the dentin were comparatively lower and more of compressive in nature. The underying bone experienced moderate amount of both compressive and tensile stresses but the displacement in this tissue were minimal compared to the rest.